Speakers - 2026

Title: Nutraceuticals: Scientific potential in endodontics

Abstract

This presentation focus on the emerging evidence that suggests nutraceutical supplementation could benefit endodontic outcomes by directly modulating periapical inflammation and supporting bone repair. Various bioactive compounds are being explored for their therapeutic effects in this context. Examples include resveratrol, quercetin, curcumin, omega-3 fatty acids, propolis, melatonin, and probiotics. Collectively, these nutraceuticals exhibit notable antioxidant, anti-inflammatory, and immunomodulatory properties. They can reduce oxidative stress, neutralize free radicals, and downregulate pro-inflammatory cytokines while stimulating host defense mechanisms. Ultimately, the goal of adjunctive nutraceutical therapy in endodontics is to recalibrate the host’s immune response by reducing excess pro-inflammatory mediators and tissue-degrading enzymes while enhancing anti-inflammatory factors and natural inhibitory molecules. Importantly, this strategy is not intended to replace standard antimicrobial disinfection of the root canal system, but to complement it by strengthening the host’s defenses and modulating the inflammatory cascade.

The audience take away from your presentation:

• The presentation aims to explain the rational of nutraceutical supplementation as potential coadjutant in endodontics.
• This approach is not intended to replace standard antimicrobial disinfection of the root canal system but to complement it.