Abstract Detail

Abstract

Aim: There is a need to develop novel technologies to enhance and support the dental implant osseointegration process. Creating nanotubular surface over Titanium alloy has shown to increase the bone-implant contact ratio and reduce the time required for loading in animal studies. The present parallel-arm, non-inferiority, randomized clinical study aims to compare the stability (ISQ) of Nanotubular and SLA dental implants over a period of 12 weeks. 

Materials and Methods: Nanotubules were created over SLA Titanium surface through anodization and standardized through annealing process. Implant surface was tested for shear forces during frictional placement. Animal testing was done successfully. DCGI clearance was obtained to conduct Pilot study in human participants. Partially edentulous participants were screened according to the inclusion and exclusion criteria and selected for each Test (nanotubular implant, NT) and Control (commercially available sandblasted acid etched implants, SB) group. Implants were placed surgically with healing abutments. Follow-up was done at 4, 8, and 12 weeks and ISQ values were measured and recorded. Osseointegrated implants were labelled as successful. 

Conclusion: Nanotubular implant surface is a novel, viable, and promising surface for Titanium dental implants, and their application should be tested further in clinical situations with compromised bone density and immediate placement and loading. Further avenues may be developed in the form of Drug eluting NT implants. 

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